Jatrophane diterpenoids from Euphorbia peplus.

Hohmann, J; Vasas, A; Günther, G; Dombi, G; Blazsó, G; Falkay, G; Máthé, I; Jerkovich, G

Hohmann, J; Vasas, A; Günther, G; Dombi, G; Blazsó, G; Falkay, G; Máthé, I; Jerkovich, G.

Afiliación

Hohmann J; Department of Pharmacognosy, Albert Szent-Györgyi Medical University, Szeged, Hungary.

Phytochemistry ; 51(5): 673-7, 1999 Jul.

Article en En | MEDLINE | ID: mdl-10392470

ABSTRACT

ABSTRACT

From the pro-inflammatory active extract of Euphorbia peplus, a new diterpene polyester (1) based on the jatrophane skeleton was isolated together with the known compounds 2-5. The irritant activities of some jatrophane diterpenes (2, 3 and 6-9) were also investigated only compound 2 was found to exert a weak pro-inflammatory activity on mouse ear.

Asunto(s)

Diterpenos/química; Irritantes/química; Extractos Vegetales/química; Animales; Diterpenos/aislamiento & purificación; Diterpenos/toxicidad; Oído; Irritantes/aislamiento & purificación; Irritantes/toxicidad; Ratones; Estructura Molecular; Extractos Vegetales/toxicidad

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Bases de datos: MEDLINE Asunto principal: Extractos Vegetales / Diterpenos / Irritantes Idioma: En Revista: Phytochemistry Año: 1999 Tipo del documento: Article País de afiliación: Hungria

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