Molluscicidal saponins from Anagallis arvensis against schistosome intermediate hosts.

Abdel-Gawad, M M; El-Amin, S M; Ohigashi, H; Watanabe, Y; Takeda, N; Sugiyama, H; Kawanaka, M

Abdel-Gawad, M M; El-Amin, S M; Ohigashi, H; Watanabe, Y; Takeda, N; Sugiyama, H; Kawanaka, M.

Afiliación

Abdel-Gawad MM; Theodor Bilharz Research Institute, Giza, Egypt. mkawan@nih.go.jp

Jpn J Infect Dis ; 53(1): 17-9, 2000 Feb.

Article en En | MEDLINE | ID: mdl-10777853

ABSTRACT

ABSTRACT

The molluscicidal activity of saponins isolated from the plant Anagallis arvensis (Primulaceae) was studied against schistosome intermediate hosts, Biomphalaria glabrata and Oncomelania quadrasi. @Strong molluscicidal activity was found in two compounds called desglucoanagalloside B and anagalloside B. Their structures were identified on the basis of chemical and spectroscopic analyses and their activities are comparable to that of the synthetic molluscicide, niclosamide.

Asunto(s)

Biomphalaria/efectos de los fármacos; Moluscos/efectos de los fármacos; Moluscocidas/química; Ácido Oleanólico/análogos & derivados; Plantas Medicinales/química; Saponinas/química; Schistosoma; Triterpenos; Animales; Espectroscopía de Resonancia Magnética; Modelos Químicos; Moluscos/parasitología; Niclosamida/química; Niclosamida/farmacología; Saponinas/farmacología; Espectrometría de Masa Bombardeada por Átomos Veloces

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Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas Asunto principal: Ácido Oleanólico / Plantas Medicinales / Saponinas / Schistosoma / Triterpenos / Biomphalaria / Moluscos / Moluscocidas Idioma: En Revista: Jpn J Infect Dis Año: 2000 Tipo del documento: Article País de afiliación: Egipto

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