New triterpenes, myrrhanol A and myrrhanone A, from guggul-gum resins, and their potent anti-inflammatory effect on adjuvant-induced air-pouch granuloma of mice.
Bioorg Med Chem Lett
; 11(8): 985-9, 2001 Apr 23.
Article
en En
| MEDLINE
| ID: mdl-11327606
ABSTRACT
Myrrhanol A, a new triterpene isolated from guggul (Balsamodendron or Commiphora mukul Hook.)-gum resin, displays a potent anti-inflammatory effect on exudative pouch fluid, angiogenesis, and granuloma weights in adjuvant-induced air-pouch granuloma of mice. Its effects were more marked than those of hydrocortisone and the 50% aqueous methanolic extract of the crude drug. Myrrhanol A is a plausible candidate for a potent anti-inflammatory agent.
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Bases de datos:
MEDLINE
Asunto principal:
Triterpenos
/
Exudados y Transudados
/
Granuloma
/
Antiinflamatorios
/
Neovascularización Patológica
Idioma:
En
Revista:
Bioorg Med Chem Lett
Año:
2001
Tipo del documento:
Article
País de afiliación:
Japón