[Synthesis and antibacterial activity of the new 9-aminoacridine, 10,11-dihydro-5H-dibenzo[b,f]azepine, polyfluoro 5,6-dihydro-1,3,5-oxadiazine derivatives]. / Sintez i issledovanie antibacterial'noi aktivnosti novykh proizvodnykh 9-aminoakridina, 10,11-digidro-5H-dibenzo[b,f]azepina, poliftorirovannykh 5,6-digidro-1,3,5-oksadiazinov.
Antibiot Khimioter
; 46(10): 6-10, 2001.
Article
en Ru
| MEDLINE
| ID: mdl-11881193
ABSTRACT
Screening among 9-aminoacridine, 10,11-dihydro-5H-dibenz[b, f]azepine and polyfluoro 5,6-dihydro-1,3,5-oxadiazine derivatives allowed to isolate compounds with potential antibacterial activity. Schemes of the active compounds synthesis are given. The most important is the estimation of the oxydiazines activity against gram-positive microorganisms including methicillin-resistant staphylococci. Special attention is paid to the activity of iminodibenzyl derivatives against multiresistant gram-negative microorganisms.
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Bases de datos:
MEDLINE
Asunto principal:
Aminoacridinas
/
Antibacterianos
Idioma:
Ru
Revista:
Antibiot Khimioter
Año:
2001
Tipo del documento:
Article