Topical estrogens combined with argon plasma coagulation in the management of epistaxis in hereditary hemorrhagic telangiectasia.
Ann Otol Rhinol Laryngol
; 111(3 Pt 1): 222-8, 2002 Mar.
Article
en En
| MEDLINE
| ID: mdl-11913682
ABSTRACT
The aim of this study was to assess the value of topically applied estrogens in patients with hereditary hemorrhagic telangiectasia. Twenty-six patients with this disorder were treated with argon plasma coagulation and randomized into 2 groups group A, which had postoperative application of estriol ointment (n = 14), and group B, which had postoperative application of dexpanthenol ointment (n = 12). Over a period of 12 months, the frequency and intensity of bleeding, the patient's satisfaction, and the success of the treatment were evaluated with a questionnaire. Before the operation, more than 90% of the patients in both groups complained of daily episodes of epistaxis. Twelve months after treatment, the frequency and intensity of bleeding had significantly decreased in group A as compared to group B. Of the patients in group A, 93% were satisfied with the treatment. Of the patients in group B, only 42% were satisfied with the treatment. In both groups, more than 90% of the patients were willing to undergo the same treatment again. The combined treatment approach with argon plasma coagulation and topical estriol enables us to significantly prolong the hemorrhage-free interval.
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Bases de datos:
MEDLINE
Asunto principal:
Ácido Pantoténico
/
Telangiectasia Hemorrágica Hereditaria
/
Epistaxis
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Coagulación con Láser
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Estriol
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
/
Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Idioma:
En
Revista:
Ann Otol Rhinol Laryngol
Año:
2002
Tipo del documento:
Article
País de afiliación:
Alemania