[Effects of Kamikihi-To on autonomic imbalances in SART-stressed (repeated cold-stressed) mice].
Nihon Yakurigaku Zasshi
; 100(2): 157-63, 1992 Aug.
Article
en Ja
| MEDLINE
| ID: mdl-1427499
ABSTRACT
The effects of Kamikihi-To (KMK), a traditional Chinese medicine, on autonomic imbalances were evaluated in SART-stressed (repeated cold-stressed) mice. These animals exhibited decreases in pain threshold and contraction of duodenum by acetylcholine, and they showed changes in their electrocardiogram and hematological parameters. All symptoms are thought to be caused by dysautonomia. KMK in dosages of 0.5 and 1.0 g/kg were administered to mice once a day for 8 consecutive days. SART stress was induced from the second day. KMK prevented the decrease in the pain threshold and contraction of the duodenum, although it had no effect on the electrocardiographic or hematological changes. KMK had no similar effect on unstressed mice. This data suggests that KMK might be useful for the treatment of clinical autonomic imbalances.
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Bases de datos:
MEDLINE
Medicinas Tradicionales:
Medicinas_tradicionales_de_asia
/
Medicina_china
Métodos Terapéuticos y Terapias MTCI:
Terapias_biologicas
Asunto principal:
Enfermedades del Sistema Nervioso Autónomo
/
Medicamentos Herbarios Chinos
Idioma:
Ja
Revista:
Nihon Yakurigaku Zasshi
Año:
1992
Tipo del documento:
Article
País de afiliación:
Japón