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[Reactivity of the liver to administration of cholic acid to rats subjected to polychloropinene expsoure for a long time]. / Reaktivnost' pecheni na vvedenie kholevoi kisloty u krys, podvergavshikhsia dlitel'nomu vozdeistviiu polikhlorpinena.
Farmakol Toksikol ; 40(3): 374-6, 1977.
Article en Ru | MEDLINE | ID: mdl-143372
It was found that in healthy rats cholic acid caused a moderately increased intensity of bile secretion and raised the content of bile acids in it. In animals with toxic hepatitis produced by a long-term action of the chemical poison polychlorpinene in a dose of 1/10 DL50 and following introduction to such rats of cholic acid in a dose of 30 mg/100 g an intensified elinination of cholates and cholesterol excretion were evident. Combined action of polychlorpinene and cholic acid was conductive to a reduced conjugation of cholic acid with taurine and to a greater conjugation with glycine, this being attended by an increased content of free bile acids in the bile.
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Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas / Aromoterapia Asunto principal: Terpenos / Bilis / Ácidos Cólicos / Enfermedad Hepática Inducida por Sustancias y Drogas / Insecticidas Idioma: Ru Revista: Farmakol Toksikol Año: 1977 Tipo del documento: Article
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Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas / Aromoterapia Asunto principal: Terpenos / Bilis / Ácidos Cólicos / Enfermedad Hepática Inducida por Sustancias y Drogas / Insecticidas Idioma: Ru Revista: Farmakol Toksikol Año: 1977 Tipo del documento: Article