Adrenocortical adenoma associated with inadequately treated congenital adrenal hyperplasia.
J Pediatr Endocrinol Metab
; 16(9): 1311-4, 2003 Dec.
Article
en En
| MEDLINE
| ID: mdl-14714757
ABSTRACT
We report a 6 year-old boy with the simple virilizing form of 21-hydroxylase deficiency in whom an adrenal adenoma developed following 5 years of steroid treatment. Extremely high levels of basal serum 17alpha-hydroxyprogesterone as well as an exaggerated response of 17alpha-hydroxyprogesterone to adrenocorticotropic hormone confirmed congenital adrenal hyperplasia at 7 years of age. Initially elevated serum steroid levels were restrained by high dose hydrocortisone therapy, but he chronically tended to take inadequate doses of glucocorticoid. At 12 years of age an adenoma was found in the cortex of the hyperplastic right adrenal gland. The importance of early diagnosis and compliance with medication in the simple virilizing form of 21-hydroxylase deficiency is stressed.
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Bases de datos:
MEDLINE
Asunto principal:
Insuficiencia del Tratamiento
/
Hiperplasia Suprarrenal Congénita
/
Adenoma Corticosuprarrenal
Tipo de estudio:
Diagnostic_studies
/
Risk_factors_studies
/
Screening_studies
Idioma:
En
Revista:
J Pediatr Endocrinol Metab
Año:
2003
Tipo del documento:
Article
País de afiliación:
Turquía