Brain activity during stimulation of the trigeminal nerve with noxious heat.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
; 102(6): 750-7, 2006 Dec.
Article
en En
| MEDLINE
| ID: mdl-17138177
ABSTRACT
OBJECTIVE:
The aim of this study was to observe areas of brain activation with painful hot stimulation to the trigeminal nerve. STUDYDESIGN:
Nine healthy pain-free women (mean age 26.2 +/- 6.9 yrs) with a natural, regular menstrual cycle participated in the study. Whole-brain functional magnetic resonance imaging (fMRI) data were acquired for each participant on day 2 or 3 after the onset of menses using echo-planar imaging at 1.5T with near-isotropic spatial resolution and a temporal resolution of 4 s.RESULTS:
Whole-brain fMRI with a Peltier thermode inside the head coil yielded a feasible imaging protocol with little disturbance from the thermode. Painful thermal stimulation of the left trigeminal system activated discrete brain regions within the insula, cingulate gyrus, thalamus, inferior parietal lobe/postcentral gyrus, right middle and inferior frontal gyri, cuneus, precuneus, and precentral gyrus.CONCLUSION:
Painful stimulation of the trigeminal nerve resulted in activation of similar brain areas generally known for pain processing of painful peripheral stimulation.
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Bases de datos:
MEDLINE
Asunto principal:
Dolor
/
Tálamo
/
Nervio Trigémino
/
Mapeo Encefálico
/
Cerebelo
/
Corteza Cerebral
Idioma:
En
Revista:
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
Año:
2006
Tipo del documento:
Article
País de afiliación:
Estados Unidos