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Massive acute haemolysis and severe neonatal hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient preterm triplets.
Shah, Varsha A; Yeo, Cheo Lian.
Afiliación
  • Shah VA; Department of Neonatal and Developmental Medicine, Singapore General Hospital, Singapore. varsha.atul.shah@sgh.com.sg
J Paediatr Child Health ; 43(5): 411-3, 2007 May.
Article en En | MEDLINE | ID: mdl-17489836
Premature triplets (2 boys and 1 girl) were delivered at 34 weeks, with both boys identified as Glucose-6-phosphate dehydrogenase (G6PD) deficient. Despite having similar quantitative levels of G6PD in their cord blood, only one boy had severe hyperbilirubinemia and anaemia caused by acute haemolysis requiring exchange transfusion. G6PD-deficient infants with the similar genetic, demographic, maternal, clinical factors and G6PD quantification levels can have different severity of presentation of neonatal jaundice in similar environmental set up. This supports the massive acute haemolysis can occur in infant with G6PD deficiency in the absence of any obvious blood group incompatibilities, infection, or ingestion of oxidising agents known to trigger haemolysis.
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Bases de datos: MEDLINE Asunto principal: Trillizos / Nacimiento Prematuro / Hiperbilirrubinemia Neonatal / Glucosafosfato Deshidrogenasa / Deficiencia de Glucosafosfato Deshidrogenasa / Hemólisis Tipo de estudio: Prognostic_studies País/Región como asunto: Asia Idioma: En Revista: J Paediatr Child Health Año: 2007 Tipo del documento: Article País de afiliación: Singapur
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Bases de datos: MEDLINE Asunto principal: Trillizos / Nacimiento Prematuro / Hiperbilirrubinemia Neonatal / Glucosafosfato Deshidrogenasa / Deficiencia de Glucosafosfato Deshidrogenasa / Hemólisis Tipo de estudio: Prognostic_studies País/Región como asunto: Asia Idioma: En Revista: J Paediatr Child Health Año: 2007 Tipo del documento: Article País de afiliación: Singapur