Diagnosis and treatment of pulmonary mucosa-associated lymphoid tissue lymphoma.
Chin Med J (Engl)
; 120(8): 648-51, 2007 Apr 20.
Article
en En
| MEDLINE
| ID: mdl-17517178
ABSTRACT
BACKGROUND:
Primary non-Hodgkin's lymphoma in lung is very rare, and the most common among them is mucosa-associated lymphoid tissue lymphoma (MALToma), whose clinical features and laboratory characteristics are poorly defined, making diagnosis difficult. The purpose of this study was to study the diagnosis and treatment of pulmonary MALToma.METHODS:
The clinical data of 12 patients treated for MALToma between August 1992 and December 2005 were analyzed.RESULTS:
No specific symptoms or signs, or results of bronchoscopy, ultrasonagraphy or bone marrow examination could be found in the 12 patients. Only radiography was useful in diagnosis, though the final diagnosis of all the patients was based on histology and immunohistochemistry. Two patients also had gastric MALToma. Operations were performed on 6 patients, including 5 radical operations and 1 partial resection 4 patients also received adjuvant chemotherapy. One patient experienced recurrence 152 months after the operation, while the other 5 patients have survived disease-free. Four patients were treated with chemotherapy alone, two of whom experienced complete remission and the others partial remission. The final 2 patients received no treatment and had survived for 7 and 27 months respectively. All the patients were still alive at the most recent follow-up, 7 to 160 months (mean 71.3 months).CONCLUSIONS:
Except radiography, no specific clinical manifestations could be identified for pulmonary MALToma. The final diagnosis should be based on histology and immunohistochemistry. Several treatment methods can be used to achieve good outcomes.
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Bases de datos:
MEDLINE
Métodos Terapéuticos y Terapias MTCI:
Terapias_manuales
/
Masoterapia
Asunto principal:
Linfoma de Células B de la Zona Marginal
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Chin Med J (Engl)
Año:
2007
Tipo del documento:
Article
País de afiliación:
China