Sorbifolivaltrates A-D, diene valepotriates from Valeriana sorbifolia(1).
J Nat Prod
; 70(12): 2045-8, 2007 Dec.
Article
en En
| MEDLINE
| ID: mdl-18052324
ABSTRACT
Four new diene valepotriates, sorbifolivaltrates A-D ( 1- 4), and the known compounds isovaltrate ( 5), valtrate ( 6), seneciovaltrate ( 7), valtrate hydrine B3 ( 8), and valtrate hydrine B7 ( 9), have been isolated by bioassay-guided fractionation of the cytotoxic hexanes and methyl ethyl ketone crude extracts of the aerial parts of Valeriana sorbifolia occurring in the Sonoran desert. The structures of 1- 4 were determined on the basis of their high-resolution mass spectrometric and NMR spectroscopic data. All compounds exhibited weak to moderate cytotoxicity against the human metastatic prostate cancer cell line, PC-3M.
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Bases de datos:
MEDLINE
Métodos Terapéuticos y Terapias MTCI:
Terapias_biologicas
Asunto principal:
Plantas Medicinales
/
Valeriana
/
Iridoides
/
Antineoplásicos Fitogénicos
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Nat Prod
Año:
2007
Tipo del documento:
Article
País de afiliación:
Estados Unidos