Treatment of experimental periodontal disease by photodynamic therapy in immunosuppressed rats.
J Clin Periodontol
; 36(3): 219-28, 2009 Mar.
Article
en En
| MEDLINE
| ID: mdl-19236534
ABSTRACT
BACKGROUND AND OBJECTIVE:
The aim of this study was to compare photodynamic therapy (PDT) as an adjunctive treatment of induced periodontitis with scaling and root planing (SRP) in dexamethasone-inhibited rats. MATERIAL ANDMETHODS:
The animals were divided into two groups ND (n=90), saline solution treatment; D (n=90), dexamethasone treatment. In the ND and D Groups, periodontal disease was ligature-induced at the first mandibular molar. After 7 days, the ligature was removed and all animals received SRP and were divided according to the following treatments SRP, saline solution; Toluidine Blue-O (TBO), phenothiazinium dye; and PDT, TBO and laser irradiation. Ten animals in each treatment were killed at 7, 15 and 30 days. The radiographic and histometric values were statistically analysed.RESULTS:
In the ND and D Groups, radiographic analysis showed less bone loss in animals treated by PDT in all the experimental periods than SRP and TBO at 15 days (p<0.05). After a histometric analysis was carried out in the ND and D groups, the animals treated by PDT showed less bone loss in all periods than SRP and TBO after 15 days (p<0.05).CONCLUSIONS:
The PDT was an effective adjunctive treatment of induced periodontitis compared with SRP in dexamethasone-inhibited rats.
Texto completo:
1
Bases de datos:
MEDLINE
Métodos Terapéuticos y Terapias MTCI:
Terapias_energeticas
Asunto principal:
Periodontitis
/
Fotoquimioterapia
/
Cloruro de Tolonio
/
Raspado Dental
/
Fármacos Fotosensibilizantes
Tipo de estudio:
Etiology_studies
Idioma:
En
Revista:
J Clin Periodontol
Año:
2009
Tipo del documento:
Article
País de afiliación:
Brasil