Extract of passion fruit (Passiflora edulis) seed containing high amounts of piceatannol inhibits melanogenesis and promotes collagen synthesis.
J Agric Food Chem
; 58(20): 11112-8, 2010 Oct 27.
Article
en En
| MEDLINE
| ID: mdl-20822151
ABSTRACT
The effect of passion fruit, the fruit of Passiflora edulis , on melanin inhibition and collagen synthesis was studied using cultured human melanoma and fibroblast cells. Passion fruit was divided into three parts, rind (PF-R), pulp (PF-P), and seed (PF-S), and each part was extracted using 80% ethanol. The concentration of polyphenols was higher in PF-S than in PF-R or PF-P. Treatment of melanoma cells with PF-S led to inhibition of melanogenesis. In addition, the production of total soluble collagen was elevated in dermal fibroblast cells cultured in the presence of PF-S. PF-R and PF-P did not yield these effects. Furthermore, the removal of polyphenols from PF-S led to the abolishment of the effects described above. We discovered that piceatannol (3,4,3',5'-tetrahydroxy-trans-stilbene) is present in passion fruit seeds in large amounts and that this compound is the major component responsible for the PF-S effects observed on melanogenesis and collagen synthesis.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Semillas
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Estilbenos
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Extractos Vegetales
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Colágeno
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Passiflora
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Melaninas
Idioma:
En
Revista:
J Agric Food Chem
Año:
2010
Tipo del documento:
Article
País de afiliación:
Japón