Autoimmune syndrome induced by adjuvants (ASIA) in the Middle East: morphea following silicone implantation.
Lupus
; 21(2): 136-9, 2012 Feb.
Article
en En
| MEDLINE
| ID: mdl-22235043
ABSTRACT
Morphea and other scleroderma-like skin conditions are occasionally linked with exposure to chemical compounds such as silicone. We treated a 56-year-old woman with generalized severe skin induration accompanied with systemic symptoms and peripheral eosinophilia, which appeared 2.5 years after breast silicone implantation and abdominal liposuction. Blood test results and histopathological examination of her skin suggested the diagnosis of morphea overlapping with eosinophilic fasciitis. Her skin disease was presumed to be an autoimmune reaction to silicone implantation. While the removal of the implants did not improve her illness, treatment with 1 mg/kg prednisone and PUVA bath was initiated, with some improvement. This patient illustrates an example of ASIA (Autoimmune Syndrome Induced by Adjuvants), as her disease appeared following exposure to an adjuvant stimulus, with 'typical', although not well-defined, autoimmune manifestations.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Esclerodermia Localizada
/
Siliconas
/
Enfermedades Autoinmunes
/
Adyuvantes Inmunológicos
/
Implantes de Mama
Tipo de estudio:
Etiology_studies
País/Región como asunto:
Asia
Idioma:
En
Revista:
Lupus
Año:
2012
Tipo del documento:
Article
País de afiliación:
Israel