Are mould hepatotoxins responsible for kava hepatotoxicity?
Phytother Res
; 26(11): 1768-70, 2012 Nov.
Article
en En
| MEDLINE
| ID: mdl-22319018
ABSTRACT
Previous studies with kava components such as kavalactones, pipermethystine and flavokavain B have demonstrated hepatotoxicity from these constituents. Regardless, there has recently been speculation that adulterants or impurities such as the mould hepatotoxin aflatoxin are a more likely cause of kava hepatotoxicity, despite a paucity of supporting evidence. Although there is limited similarity between acute kava hepatotoxicity and acute aflatoxicosis, and background levels of aflatoxin have been detected in kava samples, unless epidemiological investigations can uncover direct evidence implicating mould hepatotoxins, it remains more likely that chemical constituents of kava are the cause of the hepatotoxicity from kava.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Kava
/
Aflatoxinas
/
Enfermedad Hepática Inducida por Sustancias y Drogas
/
Hongos
Idioma:
En
Revista:
Phytother Res
Año:
2012
Tipo del documento:
Article
País de afiliación:
Australia