Vitamin D and type 2 diabetes mellitus.
J Clin Pharm Ther
; 38(2): 81-4, 2013 Apr.
Article
en En
| MEDLINE
| ID: mdl-23216626
ABSTRACT
WHAT IS KNOWN AND OBJECTIVE:
The deleterious effect of vitamin D deficiency on bone health has long been known. More recent studies suggest a deleterious effect of low vitamin D (hypovitaminosis D) on general health. And specific studies propose an association between hypovitaminosis D and the aetiology and progression of type 2 diabetes (T2DM). Given a commonly assumed lack of toxicity of vitamin D, routine measurement of plasma vitamin D and supplementation is rapidly becoming accepted general practice.COMMENT:
Authoritative practice guidelines have raised the level of vitamin D that is to be considered minimal for optimum health. This recommendation was based on a wealth of information and definitive evidence for skeletal benefits of vitamin D, but there was a lack of compelling evidence that hypovitaminosis D is causally related to extra-skeletal health outcomes such as diabetes. Hence, vitamin D supplementation for the purpose of achieving a level consistent with good health is evidence based, but measurement and supplementation for the purpose of preventing or treating T2DM is not. WHAT IS NEW ANDCONCLUSION:
Although the maintenance of adequate vitamin D levels is desirable for all patients, we conclude that routine measurement of vitamin D level in every patient or initiating high-dose supplementation for the purpose of preventing or treating T2DM is not evidence based.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Vitamina D
/
Deficiencia de Vitamina D
/
Diabetes Mellitus Tipo 2
Tipo de estudio:
Guideline
Idioma:
En
Revista:
J Clin Pharm Ther
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos