Underestimating the toxicological challenges associated with the use of herbal medicinal products in developing countries.
Biomed Res Int
; 2013: 804086, 2013.
Article
en En
| MEDLINE
| ID: mdl-24163821
ABSTRACT
Various reports suggest a high contemporaneous prevalence of herb-drug use in both developed and developing countries. The World Health Organisation indicates that 80% of the Asian and African populations rely on traditional medicine as the primary method for their health care needs. Since time immemorial and despite the beneficial and traditional roles of herbs in different communities, the toxicity and herb-drug interactions that emanate from this practice have led to severe adverse effects and fatalities. As a result of the perception that herbal medicinal products have low risk, consumers usually disregard any association between their use and any adverse reactions hence leading to underreporting of adverse reactions. This is particularly common in developing countries and has led to a paucity of scientific data regarding the toxicity and interactions of locally used traditional herbal medicine. Other factors like general lack of compositional and toxicological information of herbs and poor quality of adverse reaction case reports present hurdles which are highly underestimated by the population in the developing world. This review paper addresses these toxicological challenges and calls for natural health product regulations as well as for protocols and guidance documents on safety and toxicity testing of herbal medicinal products.
Texto completo:
1
Bases de datos:
MEDLINE
Métodos Terapéuticos y Terapias MTCI:
Terapias_biologicas
/
Plantas_medicinales
Asunto principal:
Administración Farmacéutica
/
Plantas Medicinales
/
Preparaciones de Plantas
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Medicina de Hierbas
/
Interacciones de Hierba-Droga
/
Fitoterapia
Tipo de estudio:
Guideline
/
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Biomed Res Int
Año:
2013
Tipo del documento:
Article
País de afiliación:
Mauricio