[Simultaneous determination of six ingredients in Huoxiang Zhengqi oral liquid by UPLC].
Zhongguo Zhong Yao Za Zhi
; 38(14): 2314-7, 2013 Jul.
Article
en Zh
| MEDLINE
| ID: mdl-24199562
ABSTRACT
OBJECTIVE:
To develop a UPLC method for the simultaneous determination of liquiritin, narirutin, hesperidin, ammonium glycyrrhetate, honokiol and magnolol in Huoxiang Zhengqi oral liquid.METHOD:
A Zorbax Eclipse C18 column was used with the mobile phase of acetonitrile and 0. 05% phosphate acid by gradient elution at the detection wavelength of 220 nm. The flow rate was 0.42 mL x min(-1) and the column temperature was 30 degrees C.RESULT:
The calibration curves were linear in the ranges of 0.001 7-0.034, 0.003 4-0.068, 0.006 4-0.128, 0.012 8-0.256, 0.003 2-0.064, 0.006 4-0.128 microg, respectively. The average recoveries were 103.3%, 98.39%, 98.29%, 102.1%, 98.45%, 102.2% with RSDs of 2.1%,1.0%, 0.50%, 2.3%, 0.9%, 2.0%, respectively.CONCLUSION:
The UPLC method was simple, rapid and accurate, it could be used for quality control of Huoxiang Zhengqi oral liquid.
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Bases de datos:
MEDLINE
Medicinas Tradicionales:
Medicinas_tradicionales_de_asia
/
Medicina_china
Asunto principal:
Medicamentos Herbarios Chinos
/
Cromatografía Líquida de Alta Presión
Idioma:
Zh
Revista:
Zhongguo Zhong Yao Za Zhi
Año:
2013
Tipo del documento:
Article
País de afiliación:
China