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Antimalarial 4(1H)-pyridones bind to the Qi site of cytochrome bc1.
Capper, Michael J; O'Neill, Paul M; Fisher, Nicholas; Strange, Richard W; Moss, Darren; Ward, Stephen A; Berry, Neil G; Lawrenson, Alexandre S; Hasnain, S Samar; Biagini, Giancarlo A; Antonyuk, Svetlana V.
Afiliación
  • Capper MJ; Molecular Biophysics Group, Institute of Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool L69 7ZB, United Kingdom;
  • O'Neill PM; Department of Chemistry, Faculty of Science and Engineering, University of Liverpool, Liverpool L69 7ZB, United Kingdom; and.
  • Fisher N; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom.
  • Strange RW; Molecular Biophysics Group, Institute of Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool L69 7ZB, United Kingdom;
  • Moss D; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom.
  • Ward SA; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom.
  • Berry NG; Department of Chemistry, Faculty of Science and Engineering, University of Liverpool, Liverpool L69 7ZB, United Kingdom; and.
  • Lawrenson AS; Department of Chemistry, Faculty of Science and Engineering, University of Liverpool, Liverpool L69 7ZB, United Kingdom; and.
  • Hasnain SS; Molecular Biophysics Group, Institute of Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool L69 7ZB, United Kingdom; s.s.hasnain@liverpool.ac.uk antonyuk@liverpool.ac.uk biagini@liverpool.ac.uk.
  • Biagini GA; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom s.s.hasnain@liverpool.ac.uk antonyuk@liverpool.ac.uk biagini@liverpool.ac.uk.
  • Antonyuk SV; Molecular Biophysics Group, Institute of Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool L69 7ZB, United Kingdom; s.s.hasnain@liverpool.ac.uk antonyuk@liverpool.ac.uk biagini@liverpool.ac.uk.
Proc Natl Acad Sci U S A ; 112(3): 755-60, 2015 Jan 20.
Article en En | MEDLINE | ID: mdl-25564664
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Texto completo: 1 Bases de datos: MEDLINE Medicinas Tradicionales: Medicinas_tradicionales_de_asia / Medicina_china Asunto principal: Piridonas / Complejo III de Transporte de Electrones / Antimaláricos Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article
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Texto completo: 1 Bases de datos: MEDLINE Medicinas Tradicionales: Medicinas_tradicionales_de_asia / Medicina_china Asunto principal: Piridonas / Complejo III de Transporte de Electrones / Antimaláricos Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article