Upregulation of arginase activity contributes to intracellular ROS production induced by high glucose in H9c2 cells.

Zhou, Lu; Sun, Chuan-Bo; Liu, Chao; Fan, Yue; Zhu, Hong-Yi; Wu, Xiao-Wei; Hu, Liang; Li, Qing-Ping

Zhou, Lu; Sun, Chuan-Bo; Liu, Chao; Fan, Yue; Zhu, Hong-Yi; Wu, Xiao-Wei; Hu, Liang; Li, Qing-Ping.

Afiliación

Zhou L; Department of Pharmacology, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University Nanjing, P. R. China.
Sun CB; Department of Pharmacology, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University Nanjing, P. R. China.
Liu C; Department of Pharmacology, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University Nanjing, P. R. China.
Fan Y; Department of Pharmacology, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University Nanjing, P. R. China.
Zhu HY; Department of Pharmacology, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University Nanjing, P. R. China.
Wu XW; Department of Pharmacology, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University Nanjing, P. R. China.
Hu L; Department of Pharmacology, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University Nanjing, P. R. China.
Li QP; Department of Pharmacology, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University Nanjing, P. R. China.

Int J Clin Exp Pathol ; 8(3): 2728-36, 2015.

Article en En | MEDLINE | ID: mdl-26045778

Asunto(s)

Arginasa/metabolismo; Cardiomiopatías Diabéticas/enzimología; Glucosa/metabolismo; Miocitos Cardíacos/enzimología; Estrés Oxidativo; Especies Reactivas de Oxígeno/metabolismo; Animales; Apoptosis; Arginasa/antagonistas & inhibidores; Arginina/farmacología; Línea Celular; Cardiomiopatías Diabéticas/patología; Inhibidores Enzimáticos/farmacología; Miocitos Cardíacos/efectos de los fármacos; Miocitos Cardíacos/patología; Óxido Nítrico/metabolismo; Óxido Nítrico Sintasa/antagonistas & inhibidores; Óxido Nítrico Sintasa/metabolismo; Estrés Oxidativo/efectos de los fármacos; Ratas; Superóxidos/metabolismo; Factores de Tiempo; Regulación hacia Arriba

Palabras clave

Arginase; NOS uncoupling; cardiomyocyte; diabetes; oxidative stress

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Arginasa / Especies Reactivas de Oxígeno / Estrés Oxidativo / Miocitos Cardíacos / Cardiomiopatías Diabéticas / Glucosa Idioma: En Revista: Int J Clin Exp Pathol Año: 2015 Tipo del documento: Article

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