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Pharmacokinetics and pharmacodynamics of a human monoclonal anti-FGF23 antibody (KRN23) in the first multiple ascending-dose trial treating adults with X-linked hypophosphatemia.
Zhang, Xiaoping; Imel, Erik A; Ruppe, Mary D; Weber, Thomas J; Klausner, Mark A; Ito, Takahiro; Vergeire, Maria; Humphrey, Jeffrey; Glorieux, Francis H; Portale, Anthony A; Insogna, Karl; Carpenter, Thomas O; Peacock, Munro.
Afiliación
  • Zhang X; Kyowa Hakko Kirin Pharma Inc., Princeton, NJ, USA.
  • Imel EA; Indiana University School of Medicine, Indianapolis, IN, USA.
  • Ruppe MD; The Methodist Hospital, Houston, TX, USA.
  • Weber TJ; Duke University Medical Center, Durham, NC, USA.
  • Klausner MA; Kyowa Hakko Kirin Pharma Inc., Princeton, NJ, USA.
  • Ito T; Kyowa Hakko Kirin Pharma Inc., Princeton, NJ, USA.
  • Vergeire M; Kyowa Hakko Kirin Pharma Inc., Princeton, NJ, USA.
  • Humphrey J; Kyowa Hakko Kirin Pharma Inc., Princeton, NJ, USA.
  • Glorieux FH; Shriners Hospital for Children, Montreal, Quebec, Canada.
  • Portale AA; University of California, San Francisco, CA, USA.
  • Insogna K; Yale Center for X-Linked Hypophosphatemia, Yale University School of Medicine, New Haven, CT, USA.
  • Carpenter TO; Yale Center for X-Linked Hypophosphatemia, Yale University School of Medicine, New Haven, CT, USA.
  • Peacock M; Indiana University School of Medicine, Indianapolis, IN, USA.
J Clin Pharmacol ; 56(2): 176-85, 2016 Feb.
Article en En | MEDLINE | ID: mdl-26073451
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Texto completo: 1 Bases de datos: MEDLINE Medicinas Complementárias: Homeopatia Asunto principal: Raquitismo Hipofosfatémico Familiar / Anticuerpos Monoclonales Tipo de estudio: Prognostic_studies Idioma: En Revista: J Clin Pharmacol Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Medicinas Complementárias: Homeopatia Asunto principal: Raquitismo Hipofosfatémico Familiar / Anticuerpos Monoclonales Tipo de estudio: Prognostic_studies Idioma: En Revista: J Clin Pharmacol Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos