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Synthesis and evaluation of hedgehog signaling inhibitor with novel core system.
Ohashi, Tomohiro; Tanaka, Yuta; Shiokawa, Zenyu; Banno, Hiroshi; Tanaka, Toshio; Shibata, Sachio; Satoh, Yoshihiko; Yamakawa, Hiroko; Yamamoto, Yukiko; Hattori, Harumi; Kondo, Shigeru; Miyamoto, Maki; Tojo, Hideaki; Baba, Atsuo; Sasaki, Satoshi.
Afiliación
  • Ohashi T; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan. Electronic address: tomohiro.oohashi@takeda.com.
  • Tanaka Y; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Shiokawa Z; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Banno H; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Tanaka T; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Shibata S; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Satoh Y; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Yamakawa H; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Yamamoto Y; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Hattori H; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Kondo S; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Miyamoto M; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Tojo H; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Baba A; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Sasaki S; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan. Electronic address: satoshi.sasaki@takeda.com.
Bioorg Med Chem ; 23(15): 4777-4791, 2015 Aug 01.
Article en En | MEDLINE | ID: mdl-26094943
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Piridinas / Transducción de Señal / Proteínas Hedgehog Idioma: En Revista: Bioorg Med Chem Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Piridinas / Transducción de Señal / Proteínas Hedgehog Idioma: En Revista: Bioorg Med Chem Año: 2015 Tipo del documento: Article