Avocado Proanthocyanidins as a Source of Tyrosinase Inhibitors: Structure Characterization, Inhibitory Activity, and Mechanism.

Chai, Wei-Ming; Wei, Man-Kun; Wang, Rui; Deng, Rong-Gen; Zou, Zheng-Rong; Peng, Yi-Yuan

Chai, Wei-Ming; Wei, Man-Kun; Wang, Rui; Deng, Rong-Gen; Zou, Zheng-Rong; Peng, Yi-Yuan.

Afiliación

Chai WM; College of Life Science, and Key Laboratory of Small Functional Organic Molecule, Ministry of Education, Jiangxi Normal University , Nanchang, Jiangxi 330022, People's Republic of China.
Wei MK; College of Life Science, and Key Laboratory of Small Functional Organic Molecule, Ministry of Education, Jiangxi Normal University , Nanchang, Jiangxi 330022, People's Republic of China.
Wang R; College of Life Science, and Key Laboratory of Small Functional Organic Molecule, Ministry of Education, Jiangxi Normal University , Nanchang, Jiangxi 330022, People's Republic of China.
Deng RG; College of Life Science, and Key Laboratory of Small Functional Organic Molecule, Ministry of Education, Jiangxi Normal University , Nanchang, Jiangxi 330022, People's Republic of China.
Zou ZR; College of Life Science, and Key Laboratory of Small Functional Organic Molecule, Ministry of Education, Jiangxi Normal University , Nanchang, Jiangxi 330022, People's Republic of China.
Peng YY; College of Life Science, and Key Laboratory of Small Functional Organic Molecule, Ministry of Education, Jiangxi Normal University , Nanchang, Jiangxi 330022, People's Republic of China.

J Agric Food Chem ; 63(33): 7381-7, 2015 Aug 26.

Article en En | MEDLINE | ID: mdl-26259028

Asunto(s)

Inhibidores Enzimáticos/química; Monofenol Monooxigenasa/antagonistas & inhibidores; Persea/química; Proantocianidinas/química; Proantocianidinas/farmacología; Cromatografía de Fase Inversa/métodos; Cobre/química; Evaluación Preclínica de Medicamentos/métodos; Inhibidores Enzimáticos/farmacología; Fluorescencia; Simulación del Acoplamiento Molecular; Estructura Molecular; Monofenol Monooxigenasa/química; Monofenol Monooxigenasa/metabolismo; Proantocianidinas/aislamiento & purificación; Espectrometría de Masa por Láser de Matriz Asistida de Ionización Desorción

Palabras clave

avocado; inhibitory mechanism; molecular docking; proanthocyanidins; structure; tyrosinase inhibitors

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Monofenol Monooxigenasa / Persea / Proantocianidinas / Inhibidores Enzimáticos Idioma: En Revista: J Agric Food Chem Año: 2015 Tipo del documento: Article

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