Cytotoxic phenylpropanoid glycosides from Fagopyrum tataricum (L.) Gaertn.
Food Chem
; 132(1): 433-8, 2012 May 01.
Article
en En
| MEDLINE
| ID: mdl-26434312
ABSTRACT
Fagopyrum tataricum (L.) Gaertn (tartary buckwheat) is an ancient dicotyledonous crop belonging to Polygonaceae family. Besides its benefits for human consumption, tartary buckwheat is also an important folk medicine in China for its antioxidant, antitumour, hypotensive, hypoglycaemic and hypolipidaemic activities. Phytochemical investigation of the ethyl acetate fraction of tartary buckwheat roots led to the isolation of seven new phenylpropanoid glycosides, tatarisides A-G (1-7), together with a known phenylpropanoid glycoside, diboside A (8). Their structures were elucidated by means of spectroscopic methods. All compounds (1-8) were evaluated for their cytotoxic activity against four human cancer cell lines (A-549, HCT116, ZR-75-30 and HL-60). Tatariside C (3) was the most active compound with IC50 values of 6.44-7.49µg/ml against the four tested cell lines.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Medicinas Tradicionales:
Medicinas_tradicionales_de_asia
/
Medicina_china
Métodos Terapéuticos y Terapias MTCI:
Terapias_biologicas
Asunto principal:
Ácidos Carbocíclicos
/
Fagopyrum
/
Glicósidos
/
Antineoplásicos Fitogénicos
País/Región como asunto:
Asia
Idioma:
En
Revista:
Food Chem
Año:
2012
Tipo del documento:
Article