Chenopodium ambrosioides L. extract prevents bone loss.
Acta Cir Bras
; 30(12): 812-8, 2015 Dec.
Article
en En
| MEDLINE
| ID: mdl-26735052
ABSTRACT
PURPOSE:
To evaluate the effect of the Chenopodium ambrosioides L (mastruz) extract for preventing bone loss and bone metabolism in ovariectomized rats.METHODS:
Twelve rats were subjected to bilateral ovariectomy for inducing osteoporosis. After surgery, they were divided into two groups Ovariectomy-control group (G1, n=6), receiving 0.5 ml distilled water by gavage for 30 days, and Ovariectomy plus mastruz group (G2, n=6), receiving 0.5 ml of the hydroalcoholic extract of mastruz at 10% concentration (50mg) daily, for the same period. Then, the blood of the animals was collected for further biochemical analysis (liver function) and tibia and liver were removed for histological and histomorphometric analyses.RESULTS:
The cortical bone was significantly larger in the G2 than G1, whereas G1 presented the highest amount of adipocytes in the bone marrow (p<0.05). The blood levels of aspartate aminotransferase, triglycerides and cholesterol were significantly higher, whereas globulin and lactate dehydrogenase were smaller in G2 than G1.CONCLUSION:
The hydroalcoholic extract of mastruz has effects on bone metabolism by changing blood proteins and enzymes and preventing both bone loss and the substitution of bone marrow cells by.
Texto completo:
1
Bases de datos:
MEDLINE
Métodos Terapéuticos y Terapias MTCI:
Terapias_biologicas
Asunto principal:
Osteoporosis
/
Extractos Vegetales
/
Densidad Ósea
/
Chenopodium ambrosioides
/
Fitoterapia
Tipo de estudio:
Etiology_studies
Idioma:
En
Revista:
Acta Cir Bras
Año:
2015
Tipo del documento:
Article
País de afiliación:
Brasil