Protective effect of Rabdosia amethystoides (Benth) Hara extract on acute liver injury induced by Concanavalin A in mice through inhibition of TLR4-NF-&#954;B signaling pathway.

Zhai, Ke-Feng; Duan, Hong; Cao, Wen-Gen; Gao, Gui-Zhen; Shan, Ling-Ling; Fang, Xue-Mei; Zhao, Liang

Protective effect of Rabdosia amethystoides (Benth) Hara extract on acute liver injury induced by Concanavalin A in mice through inhibition of TLR4-NF-κB signaling pathway.

Zhai, Ke-Feng; Duan, Hong; Cao, Wen-Gen; Gao, Gui-Zhen; Shan, Ling-Ling; Fang, Xue-Mei; Zhao, Liang.

Afiliación

Zhai KF; Institute of Pharmaceutical Biotechnology, School of Biological and Food Engineering, Engineering Research Center of Special Farm Seed Production, Suzhou University, 49, Bianhe Road, Suzhou, 234000, PR China. Electronic address: kefengzhai@163.com.
Duan H; Institute of Pharmaceutical Biotechnology, School of Biological and Food Engineering, Engineering Research Center of Special Farm Seed Production, Suzhou University, 49, Bianhe Road, Suzhou, 234000, PR China. Electronic address: szxydh@163.com.
Cao WG; Institute of Pharmaceutical Biotechnology, School of Biological and Food Engineering, Engineering Research Center of Special Farm Seed Production, Suzhou University, 49, Bianhe Road, Suzhou, 234000, PR China.
Gao GZ; Institute of Pharmaceutical Biotechnology, School of Biological and Food Engineering, Engineering Research Center of Special Farm Seed Production, Suzhou University, 49, Bianhe Road, Suzhou, 234000, PR China.
Shan LL; Institute of Pharmaceutical Biotechnology, School of Biological and Food Engineering, Engineering Research Center of Special Farm Seed Production, Suzhou University, 49, Bianhe Road, Suzhou, 234000, PR China.
Fang XM; Institute of Pharmaceutical Biotechnology, School of Biological and Food Engineering, Engineering Research Center of Special Farm Seed Production, Suzhou University, 49, Bianhe Road, Suzhou, 234000, PR China.
Zhao L; Institute of Pharmaceutical Biotechnology, School of Biological and Food Engineering, Engineering Research Center of Special Farm Seed Production, Suzhou University, 49, Bianhe Road, Suzhou, 234000, PR China.

J Pharmacol Sci ; 130(2): 94-100, 2016 Feb.

Article en En | MEDLINE | ID: mdl-26823124

Asunto(s)

Enfermedad Hepática Inducida por Sustancias y Drogas/prevención & control; Concanavalina A/efectos adversos; Isodon/química; Hígado/metabolismo; FN-kappa B/metabolismo; Extractos Vegetales/farmacología; Receptor Toll-Like 4/metabolismo; Animales; Enfermedad Hepática Inducida por Sustancias y Drogas/etiología; Enfermedad Hepática Inducida por Sustancias y Drogas/genética; Regulación hacia Abajo/efectos de los fármacos; Regulación hacia Abajo/genética; Expresión Génica/efectos de los fármacos; Masculino; Ratones Endogámicos ICR; Fitoterapia; Extractos Vegetales/administración & dosificación; Extractos Vegetales/uso terapéutico; ARN Mensajero/metabolismo; Transducción de Señal/efectos de los fármacos; Transducción de Señal/genética; Receptor Toll-Like 4/genética

Palabras clave

Acute liver injury; Extract of Rabdosia amethystoides; Inflammation; Protective effect; TLR4-NF-κB signaling pathway

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Medicinas Tradicionales: Medicinas_tradicionales_de_asia / Medicina_china Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas Asunto principal: Extractos Vegetales / FN-kappa B / Concanavalina A / Isodon / Receptor Toll-Like 4 / Enfermedad Hepática Inducida por Sustancias y Drogas / Hígado Tipo de estudio: Etiology_studies Idioma: En Revista: J Pharmacol Sci Año: 2016 Tipo del documento: Article

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google