A hyperglycemic silkworm model for evaluating hypoglycemic activity of Rehmanniae Radix, an herbal medicine.
Drug Discov Ther
; 10(1): 14-8, 2016 Feb.
Article
en En
| MEDLINE
| ID: mdl-26902904
ABSTRACT
Silkworm shows hyperglycemia after intake of diet containing large amount of glucose. The hyperglycemic silkworm model is useful for evaluation of anti-diabetic drugs. A hot water extract of Rehmanniae Radix, an herbal medicine, showed hypoglycemic effect against the hyperglycemic silkworms. This method is applicable for quick and simple evaluation of the hypoglycemic activities of different batches of Rehmanniae Radix. Our findings suggest that silkworms have a lot of merit as experimental animals for evaluation of various herbal medicines.
Texto completo:
1
Bases de datos:
MEDLINE
Métodos Terapéuticos y Terapias MTCI:
Terapias_biologicas
/
Plantas_medicinales
Asunto principal:
Bombyx
/
Extractos Vegetales
/
Rehmannia
/
Diabetes Mellitus
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Descubrimiento de Drogas
/
Glucosa
/
Hipoglucemiantes
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Drug Discov Ther
Año:
2016
Tipo del documento:
Article