Aspartate attenuates intestinal injury and inhibits TLR4 and NODs/NF-&#954;B and p38 signaling in weaned pigs after LPS challenge.

Wang, Haibo; Liu, Yulan; Shi, Haifeng; Wang, Xiuying; Zhu, Huiling; Pi, Dingan; Leng, Weibo; Li, Shuang

Aspartate attenuates intestinal injury and inhibits TLR4 and NODs/NF-κB and p38 signaling in weaned pigs after LPS challenge.

Wang, Haibo; Liu, Yulan; Shi, Haifeng; Wang, Xiuying; Zhu, Huiling; Pi, Dingan; Leng, Weibo; Li, Shuang.

Afiliación

Wang H; Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, 430023, China.
Liu Y; Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, 430023, China. yulanflower@126.com.
Shi H; Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, 430023, China.
Wang X; Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, 430023, China.
Zhu H; Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, 430023, China.
Pi D; Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, 430023, China.
Leng W; Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, 430023, China.
Li S; Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, 430023, China.

Eur J Nutr ; 56(4): 1433-1443, 2017 Jun.

Article en En | MEDLINE | ID: mdl-26907088

Asunto(s)

Ácido Aspártico/farmacología; Intestinos/efectos de los fármacos; FN-kappa B/metabolismo; Proteínas Adaptadoras de Señalización NOD/metabolismo; Receptor Toll-Like 4/metabolismo; Proteínas Quinasas p38 Activadas por Mitógenos/metabolismo; Amina Oxidasa (conteniendo Cobre)/metabolismo; Animales; Caspasa 3/sangre; Regulación hacia Abajo; Intestinos/patología; Lipopolisacáridos; FN-kappa B/antagonistas & inhibidores; FN-kappa B/genética; Proteínas Adaptadoras de Señalización NOD/antagonistas & inhibidores; Proteínas Adaptadoras de Señalización NOD/genética; Fosforilación; ARN Mensajero/genética; ARN Mensajero/metabolismo; Transducción de Señal; Porcinos; Receptor Toll-Like 4/antagonistas & inhibidores; Receptor Toll-Like 4/genética; Factor de Necrosis Tumoral alfa/sangre; Destete; Proteínas Quinasas p38 Activadas por Mitógenos/antagonistas & inhibidores; Proteínas Quinasas p38 Activadas por Mitógenos/genética

Palabras clave

Aspartate; Inflammatory response; Intestine injury; Lipopolysaccharide; Weaned piglets

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: FN-kappa B / Ácido Aspártico / Proteínas Quinasas p38 Activadas por Mitógenos / Receptor Toll-Like 4 / Proteínas Adaptadoras de Señalización NOD / Intestinos Idioma: En Revista: Eur J Nutr Año: 2017 Tipo del documento: Article País de afiliación: China

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