YiQiFuMai Powder Injection ameliorates the oxygen-glucose deprivation-induced brain microvascular endothelial barrier dysfunction associated with the NF-&#954;B and ROCK1/MLC signaling pathways.

Cao, Guo-Sheng; Chen, Hong-Lin; Zhang, Yuan-Yuan; Li, Fang; Liu, Chun-Hua; Xiang, Xiang; Qi, Jin; Chai, Cheng-Zhi; Kou, Jun-Ping; Yu, Bo-Yang

YiQiFuMai Powder Injection ameliorates the oxygen-glucose deprivation-induced brain microvascular endothelial barrier dysfunction associated with the NF-κB and ROCK1/MLC signaling pathways.

Cao, Guo-Sheng; Chen, Hong-Lin; Zhang, Yuan-Yuan; Li, Fang; Liu, Chun-Hua; Xiang, Xiang; Qi, Jin; Chai, Cheng-Zhi; Kou, Jun-Ping; Yu, Bo-Yang.

Afiliación

Cao GS; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Complex Prescription of TCM, China Pharmaceutical University, Nanjing, PR China. Electronic address: caoguosheng2006@163.com.
Chen HL; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Complex Prescription of TCM, China Pharmaceutical University, Nanjing, PR China. Electronic address: chen073011@126.com.
Zhang YY; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Complex Prescription of TCM, China Pharmaceutical University, Nanjing, PR China. Electronic address: cpuzhang27@163.com.
Li F; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Complex Prescription of TCM, China Pharmaceutical University, Nanjing, PR China. Electronic address: lifang19870801@126.com.
Liu CH; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Complex Prescription of TCM, China Pharmaceutical University, Nanjing, PR China. Electronic address: 742794892@qq.com.
Xiang X; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Complex Prescription of TCM, China Pharmaceutical University, Nanjing, PR China. Electronic address: 786439572@qq.com.
Qi J; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Complex Prescription of TCM, China Pharmaceutical University, Nanjing, PR China. Electronic address: yaoyuelingxing@163.com.
Chai CZ; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Complex Prescription of TCM, China Pharmaceutical University, Nanjing, PR China. Electronic address: chaichengzhi@126.com.
Kou JP; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Complex Prescription of TCM, China Pharmaceutical University, Nanjing, PR China. Electronic address: junpingkou@cpu.edu.cn.
Yu BY; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Complex Prescription of TCM, China Pharmaceutical University, Nanjing, PR China. Electronic address: boyangyu59@163.com.

J Ethnopharmacol ; 183: 18-28, 2016 May 13.

Article en En | MEDLINE | ID: mdl-26915982

Asunto(s)

Trastornos Cerebrovasculares/tratamiento farmacológico; Medicamentos Herbarios Chinos/farmacología; Microvasos/efectos de los fármacos; FN-kappa B/metabolismo; Polvos/farmacología; Transducción de Señal/efectos de los fármacos; Quinasas Asociadas a rho/metabolismo; Animales; Encéfalo/irrigación sanguínea; Encéfalo/metabolismo; Supervivencia Celular/efectos de los fármacos; Trastornos Cerebrovasculares/metabolismo; Ciclooxigenasa 2/metabolismo; Células Endoteliales/efectos de los fármacos; Células Endoteliales/metabolismo; Glucosa/metabolismo; Molécula 1 de Adhesión Intercelular/metabolismo; Interleucina-1beta/metabolismo; Interleucina-6/metabolismo; Medicina Tradicional China/métodos; Ratones; Microvasos/metabolismo; Óxido Nítrico/metabolismo; Oxígeno/metabolismo; Factor de Transcripción ReIA/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

Ginsenoside Rb1 (PubChem CID: 71317070); Ginsenoside Rc (PubChem CID: 100018); Ginsenoside Re (PubChem CID: 73149); Ginsenoside Rf (PubChem CID: 441922); Ginsenoside Rg 6 (PubChem CID: 91895489); Ginsenoside Rg3 (PubChem CID: 9918693); Microvascular endothelial barrier; NF-κB; Oxygen-glucose deprivation; ROCK1; Schizandrin B (PubChem CID: 108130).; Schizandrol A (PubChem CID: 23915); YiQiFuMai Powder Injection (YQFM)

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Texto completo: 1 Bases de datos: MEDLINE Medicinas Tradicionales: Medicinas_tradicionales_de_asia / Medicina_china Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas Asunto principal: Polvos / Medicamentos Herbarios Chinos / Transducción de Señal / Trastornos Cerebrovasculares / FN-kappa B / Quinasas Asociadas a rho / Microvasos Tipo de estudio: Diagnostic_studies / Risk_factors_studies Idioma: En Revista: J Ethnopharmacol Año: 2016 Tipo del documento: Article

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