[The influence of stinging nettle (Urtica dioica L.) extracts on the activity of catalase in THP1 monocytes/macrophages]. / Wplyw ekstraktów z pokrzywy zwyczajnej (Urtica dioica L.) na aktywnosc katalazy w monocytach/makrofagach THP1.
Pomeranian J Life Sci
; 61(3): 315-8, 2015.
Article
en Pl
| MEDLINE
| ID: mdl-27443003
ABSTRACT
INTRODUCTION:
Stinging nettle (Urtica dioicd L.) is one of the most valuable plants used in phytotherapy. The herbal raw material is a herb (Urticae herba), leaves (Urticae folium), roots (Urticae radix) and seeds (Urticae semina). This plant is a good source of vitamins, minerals, fibre, protein and biologically active compounds with antioxidant properties. The literature provides limited information about the chemical composition and properties of the seed heads. No papers are available on the effect of extracts of this plant on catalase activity in human cells. The aim of this study was to investigate the impact of stinging nettle (Urtica dioica L.) extracts on the antioxidant activity of catalase in THP1 macrophages. MATERIAL ANDMETHODS:
Two types of extracts water and alcohol, at two different concentrations, were used in experiments. Nettle was collected in September and October in 2012 in the area of Szczecin. The collected plant material was frozen and lyophilized. After those procedures water and alcohol extracts of nettle were prepared and then added to THP1 cells. RESULTS ANDCONCLUSIONS:
The antioxidant activity of catalase was established with the spectrophotometric method. The study showed that both extracts (water and alcohol) significantly increased the antioxidant activity of catalase in THP1 cells. The increase in catalase was directly proportional to the concentration of the added alcohol extract.
Buscar en Google
Bases de datos:
MEDLINE
Asunto principal:
Semillas
/
Extractos Vegetales
/
Monocitos
/
Catalasa
/
Células Cultivadas
/
Urtica dioica
/
Macrófagos
País/Región como asunto:
Europa
Idioma:
Pl
Revista:
Pomeranian J Life Sci
Año:
2015
Tipo del documento:
Article