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Novel TIE-2 inhibitor BAY-826 displays in vivo efficacy in experimental syngeneic murine glioma models.
Schneider, Hannah; Szabo, Emese; Machado, Raquel A C; Broggini-Tenzer, Angela; Walter, Alexander; Lobell, Mario; Heldmann, Dieter; Süssmeier, Frank; Grünewald, Sylvia; Weller, Michael.
Afiliación
  • Schneider H; Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.
  • Szabo E; Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.
  • Machado RA; Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.
  • Broggini-Tenzer A; Laboratory for Molecular Radiobiology, Department of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland.
  • Walter A; GTRG Oncology II, Drug Discovery, Bayer Pharma AG, Berlin, Germany.
  • Lobell M; Medicinal Chemistry, Drug Discovery, Bayer Pharma AG, Wuppertal, Germany.
  • Heldmann D; GTRG Oncology II, Drug Discovery, Bayer Pharma AG, Berlin, Germany.
  • Süssmeier F; Medicinal Chemistry, Drug Discovery, Bayer Pharma AG, Wuppertal, Germany.
  • Grünewald S; GTRG Oncology II, Drug Discovery, Bayer Pharma AG, Berlin, Germany.
  • Weller M; Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.
J Neurochem ; 140(1): 170-182, 2017 01.
Article en En | MEDLINE | ID: mdl-27787897
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Texto completo: 1 Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas / Aromoterapia Asunto principal: Neoplasias Encefálicas / Receptor TIE-2 / Modelos Animales de Enfermedad / Glioma / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Revista: J Neurochem Año: 2017 Tipo del documento: Article País de afiliación: Suiza
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas / Aromoterapia Asunto principal: Neoplasias Encefálicas / Receptor TIE-2 / Modelos Animales de Enfermedad / Glioma / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Revista: J Neurochem Año: 2017 Tipo del documento: Article País de afiliación: Suiza