Inhibitory effect of quercetin on colorectal lung metastasis through inducing apoptosis, and suppression of metastatic ability.

Kee, Ji-Ye; Han, Yo-Han; Kim, Dae-Seung; Mun, Jeong-Geon; Park, Jinbong; Jeong, Mi-Young; Um, Jae-Young; Hong, Seung-Heon

Kee, Ji-Ye; Han, Yo-Han; Kim, Dae-Seung; Mun, Jeong-Geon; Park, Jinbong; Jeong, Mi-Young; Um, Jae-Young; Hong, Seung-Heon.

Afiliación

Kee JY; Department of Oriental Pharmacy, College of Pharmacy, Wonkwang-Oriental Medicines Research Institute, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Republic of Korea.
Han YH; Department of Oriental Pharmacy, College of Pharmacy, Wonkwang-Oriental Medicines Research Institute, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Republic of Korea.
Kim DS; Department of Oriental Pharmacy, College of Pharmacy, Wonkwang-Oriental Medicines Research Institute, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Republic of Korea.
Mun JG; Department of Oriental Pharmacy, College of Pharmacy, Wonkwang-Oriental Medicines Research Institute, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Republic of Korea.
Park J; Department of Pharmacology, College of Korean Medicine, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.
Jeong MY; Department of Oriental Pharmacy, College of Pharmacy, Wonkwang-Oriental Medicines Research Institute, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Republic of Korea; Department of Pharmacology, College of Korean Medicine, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul
Um JY; Department of Pharmacology, College of Korean Medicine, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic address: jyum@khu.ac.kr.
Hong SH; Department of Oriental Pharmacy, College of Pharmacy, Wonkwang-Oriental Medicines Research Institute, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Republic of Korea. Electronic address: jooklim@wonkwang.ac.kr.

Phytomedicine ; 23(13): 1680-1690, 2016 Dec 01.

Article en En | MEDLINE | ID: mdl-27823633

Asunto(s)

Antineoplásicos Fitogénicos/farmacología; Neoplasias Colorrectales/patología; Neoplasias Pulmonares/tratamiento farmacológico; Quercetina/farmacología; Animales; Apoptosis/efectos de los fármacos; Línea Celular Tumoral; Supervivencia Celular/efectos de los fármacos; Neoplasias Colorrectales/tratamiento farmacológico; Transición Epitelial-Mesenquimal/efectos de los fármacos; Transición Epitelial-Mesenquimal/genética; Femenino; Regulación Neoplásica de la Expresión Génica/efectos de los fármacos; Células HT29/efectos de los fármacos; Humanos; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/secundario; Metaloproteinasas de la Matriz/metabolismo; Ratones Endogámicos BALB C; Proteínas Quinasas Activadas por Mitógenos/metabolismo

Palabras clave

Apoptosis; Colorectal cancer; Lung metastasis; Mitogen-activated protein kinases; Quercetin

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Quercetina / Neoplasias Colorrectales / Neoplasias Pulmonares / Antineoplásicos Fitogénicos Idioma: En Revista: Phytomedicine Año: 2016 Tipo del documento: Article

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