Gubenyiliu II Inhibits Breast Tumor Growth and Metastasis Associated with Decreased Heparanase Expression and Phosphorylation of ERK and AKT Pathways.

Zhang, Yi; Zhang, Gan-Lin; Sun, Xu; Cao, Ke-Xin; Shang, Ya-Wen; Gong, Mu-Xin; Ma, Cong; Nan, Nan; Li, Jin-Ping; Yu, Ming-Wei; Yang, Guo-Wang; Wang, Xiao-Min

Zhang, Yi; Zhang, Gan-Lin; Sun, Xu; Cao, Ke-Xin; Shang, Ya-Wen; Gong, Mu-Xin; Ma, Cong; Nan, Nan; Li, Jin-Ping; Yu, Ming-Wei; Yang, Guo-Wang; Wang, Xiao-Min.

Afiliación

Zhang Y; Department of Oncology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China. cmdzhangyi@126.com.
Zhang GL; Department of Oncology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China. kalinezhang@163.com.
Sun X; Department of Oncology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China. jiayousx@yeah.net.
Cao KX; Department of Oncology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China. kexin309@aliyun.com.
Shang YW; School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China. zhiqiang631015@126.com.
Gong MX; School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China. gongmuxin@126.com.
Ma C; Department of Oncology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China. macong0716@sina.com.
Nan N; Department of Oncology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China. kkwp263@163.com.
Li JP; Department of Oncology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China. jin-ping.li@imbim.uu.se.
Yu MW; Department of Medical Biochemistry and Microbiology, Biomedical Center, Uppsala University, Uppsala 75123, Sweden. jin-ping.li@imbim.uu.se.
Yang GW; Department of Oncology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China. yumingwei1120@163.com.
Wang XM; Department of Oncology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China. guowangyang@sina.com.

Molecules ; 22(5)2017 May 15.

Article en En | MEDLINE | ID: mdl-28505136

Asunto(s)

Neoplasias de la Mama/tratamiento farmacológico; Neoplasias de la Mama/metabolismo; Medicamentos Herbarios Chinos/uso terapéutico; Glucuronidasa/metabolismo; Animales; Neoplasias de la Mama/enzimología; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; Quinasas MAP Reguladas por Señal Extracelular/metabolismo; Femenino; Humanos; Células MCF-7; Ratones; Fosforilación/efectos de los fármacos; Proteínas Proto-Oncogénicas c-akt/metabolismo; Transducción de Señal/efectos de los fármacos

Palabras clave

ERK and AKT pathways; Gubenyiliu II; breast tumor; growth factors; heparanase

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Texto completo: 1 Bases de datos: MEDLINE Medicinas Tradicionales: Medicinas_tradicionales_de_asia / Medicina_china Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas Asunto principal: Neoplasias de la Mama / Medicamentos Herbarios Chinos / Glucuronidasa Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Molecules Año: 2017 Tipo del documento: Article País de afiliación: China

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