Transient receptor potential canonical 5 channels plays an essential role in hepatic dyslipidemia associated with cholestasis.

Alawi, Khadija M; Tandio, David; Xu, Jin; Thakore, Pratish; Papacleovoulou, Georgia; Fernandes, Elizabeth S; Legido-Quigley, Cristina; Williamson, Catherine; Brain, Susan D

Alawi, Khadija M; Tandio, David; Xu, Jin; Thakore, Pratish; Papacleovoulou, Georgia; Fernandes, Elizabeth S; Legido-Quigley, Cristina; Williamson, Catherine; Brain, Susan D.

Afiliación

Alawi KM; BHF Cardiovascular Centre of Excellence and Centre of Integrative Biomedicine, Cardiovascular Division, King's College London, London, UK.
Tandio D; BHF Cardiovascular Centre of Excellence and Centre of Integrative Biomedicine, Cardiovascular Division, King's College London, London, UK.
Xu J; Institute of Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King's College London, London, UK.
Thakore P; BHF Cardiovascular Centre of Excellence and Centre of Integrative Biomedicine, Cardiovascular Division, King's College London, London, UK.
Papacleovoulou G; Institute of Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King's College London, London, UK.
Fernandes ES; Division of Women's Health, Women's Health Academic Centre, King's College London, London, UK.
Legido-Quigley C; BHF Cardiovascular Centre of Excellence and Centre of Integrative Biomedicine, Cardiovascular Division, King's College London, London, UK.
Williamson C; Programa de Pós-Graduação, Universidade Ceuma, São Luís, Brazil.
Brain SD; Institute of Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King's College London, London, UK.

Sci Rep ; 7(1): 2338, 2017 05 24.

Article en En | MEDLINE | ID: mdl-28539583

Asunto(s)

Colestasis/metabolismo; Dislipidemias/metabolismo; Hígado/metabolismo; Canales Catiónicos TRPC/fisiología; Animales; Ácidos y Sales Biliares/sangre; Ácidos y Sales Biliares/metabolismo; Colestasis/genética; Colesterol 7-alfa-Hidroxilasa/genética; Colesterol 7-alfa-Hidroxilasa/metabolismo; Dislipidemias/genética; Expresión Génica; Lípidos/análisis; Hígado/patología; Masculino; Ratones Endogámicos ICR; Ratones Noqueados; Canales Catiónicos TRPC/deficiencia; Canales Catiónicos TRPC/genética

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Colestasis / Dislipidemias / Canales Catiónicos TRPC / Hígado Tipo de estudio: Risk_factors_studies Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido

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