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Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.
Miller, Tyler E; Liau, Brian B; Wallace, Lisa C; Morton, Andrew R; Xie, Qi; Dixit, Deobrat; Factor, Daniel C; Kim, Leo J Y; Morrow, James J; Wu, Qiulian; Mack, Stephen C; Hubert, Christopher G; Gillespie, Shawn M; Flavahan, William A; Hoffmann, Thomas; Thummalapalli, Rohit; Hemann, Michael T; Paddison, Patrick J; Horbinski, Craig M; Zuber, Johannes; Scacheri, Peter C; Bernstein, Bradley E; Tesar, Paul J; Rich, Jeremy N.
Afiliación
  • Miller TE; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
  • Liau BB; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195, USA.
  • Wallace LC; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
  • Morton AR; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
  • Xie Q; Harvard Medical School, Boston, Massachusetts 02114, USA.
  • Dixit D; Epigenomics Program, Broad Institute, Cambridge, Massachusetts 02142, USA.
  • Factor DC; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
  • Kim LJY; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
  • Morrow JJ; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
  • Wu Q; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
  • Mack SC; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
  • Hubert CG; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
  • Gillespie SM; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
  • Flavahan WA; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
  • Hoffmann T; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195, USA.
  • Thummalapalli R; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
  • Hemann MT; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
  • Paddison PJ; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
  • Horbinski CM; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
  • Zuber J; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
  • Scacheri PC; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195, USA.
  • Bernstein BE; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
  • Tesar PJ; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195, USA.
  • Rich JN; Harvard Medical School, Boston, Massachusetts 02114, USA.
Nature ; 547(7663): 355-359, 2017 07 20.
Article en En | MEDLINE | ID: mdl-28678782
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Glioblastoma / Factores de Elongación Transcripcional / Evaluación Preclínica de Medicamentos / Terapia Molecular Dirigida Tipo de estudio: Prognostic_studies Idioma: En Revista: Nature Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Glioblastoma / Factores de Elongación Transcripcional / Evaluación Preclínica de Medicamentos / Terapia Molecular Dirigida Tipo de estudio: Prognostic_studies Idioma: En Revista: Nature Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos