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Polygonumnolides A1-B3, minor dianthrone derivatives from the roots of Polygonum multiflorum Thunb.
Yang, Jianbo; Yan, Zheng; Ren, Jin; Dai, Zhong; Ma, Shuangcheng; Wang, Aiguo; Su, Yalun.
Afiliación
  • Yang J; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, People's Republic of China.
  • Yan Z; Research and Inspection Center of Traditional Chinese Medicine and Ethnomedicine, National Institutes for Food and Drug Control, State Food and Drug Administration, Beijing, 100050, People's Republic of China.
  • Ren J; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 100102, People's Republic of China.
  • Dai Z; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, People's Republic of China.
  • Ma S; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, People's Republic of China.
  • Wang A; Research and Inspection Center of Traditional Chinese Medicine and Ethnomedicine, National Institutes for Food and Drug Control, State Food and Drug Administration, Beijing, 100050, People's Republic of China.
  • Su Y; Research and Inspection Center of Traditional Chinese Medicine and Ethnomedicine, National Institutes for Food and Drug Control, State Food and Drug Administration, Beijing, 100050, People's Republic of China. masc@nifdc.org.cn.
Arch Pharm Res ; 41(6): 617-624, 2018 Jun.
Article en En | MEDLINE | ID: mdl-28681348
ABSTRACT
Seven new dianthrone glycosides, named polygonumnolides A1-B3 (1-7), were isolated from the 70 % EtOH extract of the dried roots of Polygonum multiflorum Thunb. using column chromatography and preparative high-performance liquid chromatography. Their structures were determined by 1D and 2D NMR and mass spectroscopy. The isolated compounds were evaluated for their cytotoxic effects against KB tumor cell lines and compounds 1-4 showed moderate cytotoxicity.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Extractos Vegetales / Fallopia multiflora / Glicósidos / Antineoplásicos Fitogénicos Idioma: En Revista: Arch Pharm Res Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Extractos Vegetales / Fallopia multiflora / Glicósidos / Antineoplásicos Fitogénicos Idioma: En Revista: Arch Pharm Res Año: 2018 Tipo del documento: Article