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Heat-induced BRCA2 degradation in human tumours provides rationale for hyperthermia-PARP-inhibitor combination therapies.
van den Tempel, Nathalie; Odijk, Hanny; van Holthe, Netteke; Naipal, Kishan; Raams, Anja; Eppink, Berina; van Gent, Dik C; Hardillo, Jose; Verduijn, Gerda M; Drooger, Jan C; van Rhoon, Gerard C; Smedts, Dineke H P M; van Doorn, Helena C; Boormans, Joost L; Jager, Agnes; Franckena, Martine; Kanaar, Roland.
Afiliación
  • van den Tempel N; a Department of Molecular Genetics , Cancer Genomics Centre Netherlands Erasmus University Medical Centre , Rotterdam , The Netherlands.
  • Odijk H; a Department of Molecular Genetics , Cancer Genomics Centre Netherlands Erasmus University Medical Centre , Rotterdam , The Netherlands.
  • van Holthe N; b Department of Radiation Oncology , Erasmus MC Cancer Institute , Rotterdam , The Netherlands.
  • Naipal K; a Department of Molecular Genetics , Cancer Genomics Centre Netherlands Erasmus University Medical Centre , Rotterdam , The Netherlands.
  • Raams A; a Department of Molecular Genetics , Cancer Genomics Centre Netherlands Erasmus University Medical Centre , Rotterdam , The Netherlands.
  • Eppink B; a Department of Molecular Genetics , Cancer Genomics Centre Netherlands Erasmus University Medical Centre , Rotterdam , The Netherlands.
  • van Gent DC; a Department of Molecular Genetics , Cancer Genomics Centre Netherlands Erasmus University Medical Centre , Rotterdam , The Netherlands.
  • Hardillo J; c Department of Otolaryngology and Head and Neck Surgery , Erasmus University Medical Centre , Rotterdam , The Netherlands.
  • Verduijn GM; b Department of Radiation Oncology , Erasmus MC Cancer Institute , Rotterdam , The Netherlands.
  • Drooger JC; d Department of Medical Oncology , Ikazia Hospital , Rotterdam , The Netherlands.
  • van Rhoon GC; b Department of Radiation Oncology , Erasmus MC Cancer Institute , Rotterdam , The Netherlands.
  • Smedts DHPM; e Department of Gynaecological Oncology , Erasmus University Medical Centre , Rotterdam , The Netherlands.
  • van Doorn HC; e Department of Gynaecological Oncology , Erasmus University Medical Centre , Rotterdam , The Netherlands.
  • Boormans JL; f Department of Urology , Erasmus MC Cancer Institute , Rotterdam , The Netherlands.
  • Jager A; g Department of Medical Oncology , Erasmus MC Cancer Institute , Rotterdam , The Netherlands.
  • Franckena M; b Department of Radiation Oncology , Erasmus MC Cancer Institute , Rotterdam , The Netherlands.
  • Kanaar R; a Department of Molecular Genetics , Cancer Genomics Centre Netherlands Erasmus University Medical Centre , Rotterdam , The Netherlands.
Int J Hyperthermia ; 34(4): 407-414, 2018 06.
Article en En | MEDLINE | ID: mdl-28705099
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteína BRCA2 / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Hipertermia Inducida / Neoplasias Idioma: En Revista: Int J Hyperthermia Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteína BRCA2 / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Hipertermia Inducida / Neoplasias Idioma: En Revista: Int J Hyperthermia Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos