Polyphenols: dietary assessment and role in the prevention of cancers.
Curr Opin Clin Nutr Metab Care
; 20(6): 512-521, 2017 Nov.
Article
en En
| MEDLINE
| ID: mdl-28915128
ABSTRACT
PURPOSE OF REVIEW Polyphenols are a large and diverse family of phytochemicals widely consumed by humans. Here we summarize the latest epidemiological evidence for associations between cancer risk and polyphenol intake, taking into account difficulties in the accurate estimation of exposure. RECENT FINDINGS:
Flavonoids are the most studied subgroup of polyphenols with regard to cancer risk. In recent epidemiological studies, total flavonoid intake has rarely been associated with a reduction in cancer risk. However, isoflavones, whose main dietary source is soy foods, plausibly reduce the risk of colorectal, breast, and prostate cancers, especially in Asian countries. Findings depend heavily upon the assessment of polyphenol intake, which is usually measured by food frequency questionnaires coupled to databases of food polyphenol composition. To a lesser extent, nutritional biomarkers have been used whenever estimating associations of polyphenol intake with cancer.SUMMARY:
Polyphenol intake may mitigate cancer risk but this depends on cancer site, the subgroup of compounds under study, and accurate assessment of dietary exposure. Further work must better characterize the effects of intake of different flavonoid subclasses and begin to investigate the role of phenolic acids and other minor polyphenol classes.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Evaluación Nutricional
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Dieta
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Polifenoles
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Neoplasias
Tipo de estudio:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
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Systematic_reviews
Idioma:
En
Revista:
Curr Opin Clin Nutr Metab Care
Año:
2017
Tipo del documento:
Article
País de afiliación:
España