New 8,12;8,20-diepoxy-8,14-secopregnane hexa- and hepta-glycosides from the roots of Asclepias tuberosa.
J Nat Med
; 72(1): 347-356, 2018 Jan.
Article
en En
| MEDLINE
| ID: mdl-29177792
ABSTRACT
Previously, phytochemical investigation of the roots of Asclepias tuberosa (Asclepiadaceae) led to the isolation of some 8,12;8,20-diepoxy-8,14-secopregnane tri-, tetra-, and penta-glycosides. An additional eight new minor 8,12;8,20-diepoxy-8,14-secopregnane glycosides were afforded in the recent investigation of this plant. These glycosides consisted of six or seven 2,6-dideoxy-hexopyranoses together with the aglycone, tuberogenin. The structures of each of these compounds were established using NMR, mass spectroscopic analysis and chemical evidence. As 8,12;8,20-diepoxy-8,14-secopregnane-type glycosides were observed only in A. tuberosa, these compounds were considered to be characteristic phytochemicals of this plant.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Pregnanos
/
Raíces de Plantas
/
Asclepias
/
Glicósidos
Idioma:
En
Revista:
J Nat Med
Año:
2018
Tipo del documento:
Article
País de afiliación:
Japón