Low-protein diet supplemented with ketoacids delays the progression of diabetic nephropathy by inhibiting oxidative stress in the KKAy mice model.

Liu, Dongmei; Wu, Ming; Li, Lin; Gao, Xiang; Yang, Bo; Mei, Shuqin; Fu, Lili; Mei, Changlin

Liu, Dongmei; Wu, Ming; Li, Lin; Gao, Xiang; Yang, Bo; Mei, Shuqin; Fu, Lili; Mei, Changlin.

Afiliación

Liu D; Department of Nephrology,Shanghai Changzheng Hospital,Kidney Institute,Second Military Medical University,Shanghai,200003, People's Republic of China.
Wu M; Department of Nephrology,Shanghai Changzheng Hospital,Kidney Institute,Second Military Medical University,Shanghai,200003, People's Republic of China.
Li L; Department of Nephrology,Shanghai Changzheng Hospital,Kidney Institute,Second Military Medical University,Shanghai,200003, People's Republic of China.
Gao X; Department of Nephrology,Shanghai Changzheng Hospital,Kidney Institute,Second Military Medical University,Shanghai,200003, People's Republic of China.
Yang B; Department of Nephrology,Shanghai Changzheng Hospital,Kidney Institute,Second Military Medical University,Shanghai,200003, People's Republic of China.
Mei S; Department of Nephrology,Shanghai Changzheng Hospital,Kidney Institute,Second Military Medical University,Shanghai,200003, People's Republic of China.
Fu L; Department of Nephrology,Shanghai Changzheng Hospital,Kidney Institute,Second Military Medical University,Shanghai,200003, People's Republic of China.
Mei C; Department of Nephrology,Shanghai Changzheng Hospital,Kidney Institute,Second Military Medical University,Shanghai,200003, People's Republic of China.

Br J Nutr ; 119(1): 22-29, 2018 01.

Article en En | MEDLINE | ID: mdl-29208058

Asunto(s)

Nefropatías Diabéticas/dietoterapia; Dieta con Restricción de Proteínas; Cetoácidos/química; Estrés Oxidativo; Insuficiencia Renal Crónica/dietoterapia; Albuminuria/terapia; Animales; Diabetes Mellitus Experimental/dietoterapia; Diabetes Mellitus Experimental/metabolismo; Diabetes Mellitus Tipo 2/dietoterapia; Diabetes Mellitus Tipo 2/metabolismo; Nefropatías Diabéticas/metabolismo; Suplementos Dietéticos; Modelos Animales de Enfermedad; Membrana Basal Glomerular/metabolismo; Riñón/metabolismo; Masculino; Ratones; Ratones Endogámicos C57BL; Tamaño de los Órganos; Insuficiencia Renal Crónica/metabolismo

Palabras clave

CKD chronic kidney disease; DN diabetic nephropathy; GBM glomerular basement membrane; KA ketoacids; LPD low-protein diet; LPD+KA LPD supplemented with KA; MDA malondialdehyde; NPD normal protein diet; NT nitrotyrosin; SOD superoxide dismutase; Diabetic nephropathy; Ketoacids; Low-protein diets; Oxidative stress

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Estrés Oxidativo / Dieta con Restricción de Proteínas / Nefropatías Diabéticas / Insuficiencia Renal Crónica / Cetoácidos Idioma: En Revista: Br J Nutr Año: 2018 Tipo del documento: Article

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