Similar treatment outcomes with Ginkgo biloba extract EGb 761 and donepezil in Alzheimer's dementia in very old age: A retrospective observational study.
Int J Clin Pharmacol Ther
; 56(3): 130-133, 2018 Mar.
Article
en En
| MEDLINE
| ID: mdl-29319499
ABSTRACT
OBJECTIVE:
To provide pilot data for the safety and efficacy of EGb 761 in the oldest-old patients (aged 80 or older). MATERIALS ANDMETHODS:
In a retrospective analysis, we compared treatment outcomes with EGb 761 or donepezil over 12 months in 189 patients aged 80 years or older suffering from Alzheimer's disease (AD).RESULTS:
Over 12 months, there was no significant difference in cognitive decline, measured with the mini-mental state examination (MMSE) score, between donepezil and EGb 761 (p = 0.31). We found more adverse events in the donepezil group.CONCLUSION:
Results suggest similar effects on cognitive symptoms from the use of EGb 761 in the treatment of dementia in AD together with favorable safety compared to donepezil.â©.
Texto completo:
1
Bases de datos:
MEDLINE
Métodos Terapéuticos y Terapias MTCI:
Terapias_biologicas
Asunto principal:
Piperidinas
/
Extractos Vegetales
/
Nootrópicos
/
Enfermedad de Alzheimer
/
Indanos
Tipo de estudio:
Observational_studies
Idioma:
En
Revista:
Int J Clin Pharmacol Ther
Año:
2018
Tipo del documento:
Article