Reduced interference in working memory following mindfulness training is associated with increases in hippocampal volume.
Brain Imaging Behav
; 13(2): 366-376, 2019 Apr.
Article
en En
| MEDLINE
| ID: mdl-29549665
ABSTRACT
Proactive interference occurs when previously relevant information interferes with retaining newer material. Overcoming proactive interference has been linked to the hippocampus and deemed critical for cognitive functioning. However, little is known about whether and how this ability can be improved or about the neural correlates of such improvement. Mindfulness training emphasizes focusing on the present moment and minimizing distraction from competing thoughts and memories. It improves working memory and increases hippocampal density. The current study examined whether mindfulness training reduces proactive interference in working memory and whether such improvements are associated with changes in hippocampal volume. 79 participants were randomized to a 4-week web-based mindfulness training program or a similarly structured creative writing active control program. The mindfulness group exhibited lower proactive interference error rates compared to the active control group following training. No group differences were found in hippocampal volume, yet proactive interference improvements following mindfulness training were significantly associated with volume increases in the left hippocampus. These results provide the first evidence to suggest that (1) mindfulness training can protect against proactive interference, and (2) that these benefits are related to hippocampal volumetric increases. Clinical implications regarding the application of mindfulness training in conditions characterized by impairments to working memory and reduced hippocampal volume such as aging, depression, PTSD, and childhood adversity are discussed.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Métodos Terapéuticos y Terapias MTCI:
Terapias_mente_y_cuerpo
/
Meditacion
Asunto principal:
Imagen por Resonancia Magnética
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Atención Plena
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Hipocampo
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Memoria a Corto Plazo
Tipo de estudio:
Clinical_trials
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Risk_factors_studies
Idioma:
En
Revista:
Brain Imaging Behav
Año:
2019
Tipo del documento:
Article
País de afiliación:
Estados Unidos