Radix Paeoniae Rubra stimulates osteoclast differentiation by activation of the NF-&#954;B and mitogen-activated protein kinase pathways.

Tzeng, Huey-En; Tsai, Chun-Hao; Ho, Tin-Yun; Hsieh, Chin-Tung; Chou, Shen-Chieh; Lee, Yi-Ju; Tsay, Gregory J; Huang, Po-Hao; Wu, Yi-Ying

Radix Paeoniae Rubra stimulates osteoclast differentiation by activation of the NF-κB and mitogen-activated protein kinase pathways.

Tzeng, Huey-En; Tsai, Chun-Hao; Ho, Tin-Yun; Hsieh, Chin-Tung; Chou, Shen-Chieh; Lee, Yi-Ju; Tsay, Gregory J; Huang, Po-Hao; Wu, Yi-Ying.

Afiliación

Tzeng HE; Taipei Cancer Center, Taipei Medical University, Taipei, Taiwan.
Tsai CH; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Ho TY; Department of Internal Medicine, Division of Hematology/Oncology, Tapei Medical University Shuang-Ho Hospital, Taipei, Taiwan.
Hsieh CT; Department of Orthopedics, School of Medicine, China Medical University Hospital and China Medical University, Taichung, Taiwan.
Chou SC; Graduate Institute of Chinese Medicine, China Medical University, Taichung, Taiwan.
Lee YJ; Department of Pediatrics, Lotung Poh-Ai Hospital, I-Lan, Taiwan.
Tsay GJ; Department of Biological Science and Technology, School of Medicine, China Medical University, Taichung, Taiwan.
Huang PH; Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical University, Taichung, Taiwan.
Wu YY; Division of Immunology and Rheumatology, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.

BMC Complement Altern Med ; 18(1): 132, 2018 Apr 23.

Article en En | MEDLINE | ID: mdl-29688864

Asunto(s)

Diferenciación Celular/efectos de los fármacos; Proteínas Quinasas Activadas por Mitógenos/metabolismo; FN-kappa B/metabolismo; Osteoclastos/efectos de los fármacos; Paeonia/química; Extractos Vegetales/farmacología; Animales; Células Cultivadas; Humanos; Leucocitos Mononucleares; Ratones; Células RAW 264.7; Receptor Activador del Factor Nuclear kappa-B/metabolismo; Transducción de Señal/efectos de los fármacos

Palabras clave

Mitogen-activated protein kinase; Osteoclast; Receptor activator of nuclear factor-kappa B

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Osteoclastos / Extractos Vegetales / Diferenciación Celular / FN-kappa B / Proteínas Quinasas Activadas por Mitógenos / Paeonia Idioma: En Revista: BMC Complement Altern Med Año: 2018 Tipo del documento: Article País de afiliación: Taiwán

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