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Small Molecule Inhibitors of Metabolic Enzymes Repurposed as a New Class of Anthelmintics.
Tyagi, Rahul; Maddirala, Amarendar Reddy; Elfawal, Mostafa; Fischer, Chelsea; Bulman, Christina A; Rosa, Bruce A; Gao, Xin; Chugani, Ryan; Zhou, Mingzhou; Helander, Jon; Brindley, Paul J; Tseng, Chih-Chung; Greig, Iain R; Sakanari, Judy; Wildman, Scott A; Aroian, Raffi; Janetka, James W; Mitreva, Makedonka.
Afiliación
  • Tyagi R; McDonnell Genome Institute , Washington University School of Medicine , 4444 Forest Park Ave. , St. Louis , Missouri 63108 , United States.
  • Maddirala AR; Department of Biochemistry and Molecular Biophysics , Washington University School of Medicine , 660 S. Euclid Ave. , St. Louis , Missouri 63110 , United States.
  • Elfawal M; University of Massachusetts Medical School , 373 Plantation Street , Worcester , Massachusetts 01605 , United States.
  • Fischer C; Department of Pharmaceutical Chemistry , University of California San Francisco , 1700 4th Street , San Francisco , California 94158 , United States.
  • Bulman CA; Department of Pharmaceutical Chemistry , University of California San Francisco , 1700 4th Street , San Francisco , California 94158 , United States.
  • Rosa BA; McDonnell Genome Institute , Washington University School of Medicine , 4444 Forest Park Ave. , St. Louis , Missouri 63108 , United States.
  • Gao X; McDonnell Genome Institute , Washington University School of Medicine , 4444 Forest Park Ave. , St. Louis , Missouri 63108 , United States.
  • Chugani R; Department of Biochemistry and Molecular Biophysics , Washington University School of Medicine , 660 S. Euclid Ave. , St. Louis , Missouri 63110 , United States.
  • Zhou M; Department of Biochemistry and Molecular Biophysics , Washington University School of Medicine , 660 S. Euclid Ave. , St. Louis , Missouri 63110 , United States.
  • Helander J; Department of Biochemistry and Molecular Biophysics , Washington University School of Medicine , 660 S. Euclid Ave. , St. Louis , Missouri 63110 , United States.
  • Brindley PJ; Department of Microbiology, Immunology & Tropical Medicine and Research Center for Neglected Diseases of Poverty, School of Medicine and Health Sciences , George Washington University , 2300 Eye Street, NW, Washington , D.C. 20037 , United States.
  • Tseng CC; Kosterlitz Centre for Therapeutics , University of Aberdeen , Foresterhill, Aberdeen , AB25 2ZD , United Kingdom.
  • Greig IR; Kosterlitz Centre for Therapeutics , University of Aberdeen , Foresterhill, Aberdeen , AB25 2ZD , United Kingdom.
  • Sakanari J; Department of Pharmaceutical Chemistry , University of California San Francisco , 1700 4th Street , San Francisco , California 94158 , United States.
  • Wildman SA; UW Carbone Cancer Center, School of Medicine and Public Health , University of Wisconsin-Madison , 1111 Highland Ave. , Madison , Wisconsin 53792 , United States.
  • Aroian R; University of Massachusetts Medical School , 373 Plantation Street , Worcester , Massachusetts 01605 , United States.
  • Janetka JW; Department of Biochemistry and Molecular Biophysics , Washington University School of Medicine , 660 S. Euclid Ave. , St. Louis , Missouri 63110 , United States.
  • Mitreva M; McDonnell Genome Institute , Washington University School of Medicine , 4444 Forest Park Ave. , St. Louis , Missouri 63108 , United States.
ACS Infect Dis ; 4(7): 1130-1145, 2018 07 13.
Article en En | MEDLINE | ID: mdl-29718656
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Antihelmínticos / Nematodos Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: ACS Infect Dis Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Antihelmínticos / Nematodos Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: ACS Infect Dis Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos