Long-Term Oral Administration of Theaphenon-E Improves Cardiomyocyte Mechanics and Calcium Dynamics by Affecting Phospholamban Phosphorylation and ATP Production.

Bocchi, Leonardo; Savi, Monia; Naponelli, Valeria; Vilella, Rocchina; Sgarbi, Gianluca; Baracca, Alessandra; Solaini, Giancarlo; Bettuzzi, Saverio; Rizzi, Federica; Stilli, Donatella

Bocchi, Leonardo; Savi, Monia; Naponelli, Valeria; Vilella, Rocchina; Sgarbi, Gianluca; Baracca, Alessandra; Solaini, Giancarlo; Bettuzzi, Saverio; Rizzi, Federica; Stilli, Donatella.

Afiliación

Bocchi L; Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy.
Savi M; Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy.
Naponelli V; Department of Medicine and Surgery, University of Parma, Parma, Italy.
Vilella R; Fondazione Umberto Veronesi, Milan, Italy.
Sgarbi G; Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy.
Baracca A; Department of Biomedical and Neuromotor Sciences , University of Bologna, Bologna, Italy.
Solaini G; Department of Biomedical and Neuromotor Sciences , University of Bologna, Bologna, Italy.
Bettuzzi S; Department of Biomedical and Neuromotor Sciences , University of Bologna, Bologna, Italy.
Rizzi F; Department of Medicine and Surgery, University of Parma, Parma, Italy.
Stilli D; National Institute of Biostructure and Biosystems (INBB), Rome, Italy.

Cell Physiol Biochem ; 47(3): 1230-1243, 2018.

Article en En | MEDLINE | ID: mdl-29913456

Asunto(s)

Adenosina Trifosfato/biosíntesis; Señalización del Calcio/efectos de los fármacos; Proteínas de Unión al Calcio/metabolismo; Metabolismo Energético/efectos de los fármacos; Miocitos Cardíacos/metabolismo; Polifenoles/farmacología; Té/química; Administración Oral; Animales; Masculino; Miocitos Cardíacos/citología; Fosforilación/efectos de los fármacos; Polifenoles/química; Ratas; Ratas Wistar; ATPasas Transportadoras de Calcio del Retículo Sarcoplásmico/metabolismo

Palabras clave

Calcium dynamics; Cardiomyocyte mechanics; Catechins; Green tea extracts; Mitochondrial respiration; Phospholamban; SERCA2 activity

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Té / Proteínas de Unión al Calcio / Adenosina Trifosfato / Señalización del Calcio / Miocitos Cardíacos / Metabolismo Energético / Polifenoles Idioma: En Revista: Cell Physiol Biochem Año: 2018 Tipo del documento: Article País de afiliación: Italia

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