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Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway.
Zhou, Wenjing; Wang, Jiwei; Qi, Qichao; Feng, Zichao; Huang, Bin; Chen, Anjing; Zhang, Di; Li, Wenjie; Zhang, Qing; Bjerkvig, Rolf; Li, Xingang; Wang, Jian.
Afiliación
  • Zhou W; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Wang J; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Qi Q; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Feng Z; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Huang B; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Chen A; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Zhang D; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Li W; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Zhang Q; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Bjerkvig R; Department of Biomedicine, K G Jebsen Brain Tumor Research Center, University of Bergen, Bergen, Norway.
  • Li X; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Wang J; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
Cancer Med ; 7(9): 4729-4743, 2018 09.
Article en En | MEDLINE | ID: mdl-30079478
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Texto completo: 1 Bases de datos: MEDLINE Medicinas Tradicionales: Medicinas_tradicionales_de_asia / Medicina_china Asunto principal: Quinolizinas / Factor I del Crecimiento Similar a la Insulina / Transducción de Señal / Glioblastoma / Fosfatidilinositol 3-Quinasas / Alcaloides / Proteínas Proto-Oncogénicas c-akt / Inhibidor p27 de las Quinasas Dependientes de la Ciclina Tipo de estudio: Prognostic_studies Idioma: En Revista: Cancer Med Año: 2018 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Medicinas Tradicionales: Medicinas_tradicionales_de_asia / Medicina_china Asunto principal: Quinolizinas / Factor I del Crecimiento Similar a la Insulina / Transducción de Señal / Glioblastoma / Fosfatidilinositol 3-Quinasas / Alcaloides / Proteínas Proto-Oncogénicas c-akt / Inhibidor p27 de las Quinasas Dependientes de la Ciclina Tipo de estudio: Prognostic_studies Idioma: En Revista: Cancer Med Año: 2018 Tipo del documento: Article País de afiliación: China