Cadmium-mediated miR-30a-GRP78 leads to JNK-dependent autophagy in chicken kidney.

Shi, Qunxiang; Jin, Xi; Fan, Ruifeng; Xing, Mengyuan; Guo, Jinming; Zhang, Ziwei; Zhang, Junmin; Xu, Shiwen

Shi, Qunxiang; Jin, Xi; Fan, Ruifeng; Xing, Mengyuan; Guo, Jinming; Zhang, Ziwei; Zhang, Junmin; Xu, Shiwen.

Afiliación

Shi Q; College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, PR China.
Jin X; College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, PR China.
Fan R; College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, PR China.
Xing M; College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, PR China.
Guo J; College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, PR China.
Zhang Z; College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, PR China.
Zhang J; Institute of Animal Science, Chinese Academy of Agricultural Sciences, Scientific Observing and Experiment Station of Animal Genetic Resources and Nutrition in North China, Ministry of Agriculture, No. 2 Yuanmingyuan West Road Haidian District, Beijing 100193, PR China. Electronic address: zhjmxms@s
Xu S; College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, PR China; Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment, College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, PR

Chemosphere ; 215: 710-715, 2019 Jan.

Article en En | MEDLINE | ID: mdl-30352370

Asunto(s)

Autofagia/efectos de los fármacos; Cadmio/toxicidad; Riñón/patología; MicroARNs/metabolismo; Animales; Autofagia/genética; Cadmio/metabolismo; Pollos/metabolismo; Interacciones Farmacológicas; Chaperón BiP del Retículo Endoplásmico; Estrés del Retículo Endoplásmico/efectos de los fármacos; Proteínas de Choque Térmico/metabolismo; Riñón/metabolismo; Sistema de Señalización de MAP Quinasas; Selenio/metabolismo; Selenio/farmacología

Palabras clave

Autophagy; Cadmium; ER stress; JNK; miR-30a-GRP78

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Autofagia / Cadmio / MicroARNs / Riñón Idioma: En Revista: Chemosphere Año: 2019 Tipo del documento: Article