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Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design.
Hobson, Adrian D; Judge, Russell A; Aguirre, Ana L; Brown, Brian S; Cui, Yifang; Ding, Ping; Dominguez, Eric; DiGiammarino, Enrico; Egan, David A; Freiberg, Gail M; Gopalakrishnan, Sujatha M; Harris, Christopher M; Honore, Marie P; Kage, Karen L; Kapecki, Nicolas J; Ling, Christopher; Ma, Junli; Mack, Helmut; Mamo, Mulugeta; Maurus, Stefan; McRae, Bradford; Moore, Nigel S; Mueller, Bernhard K; Mueller, Reinhold; Namovic, Marian T; Patel, Kaushal; Pratt, Steve D; Putman, C Brent; Queeney, Kara L; Sarris, Kathy K; Schaffter, Lisa M; Stoll, Vincent; Vasudevan, Anil; Wang, Lei; Wang, Lu; Wirthl, William; Yach, Kimberly.
Afiliación
  • Hobson AD; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States.
  • Judge RA; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Aguirre AL; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Brown BS; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Cui Y; AbbVie Deutschland GmbH & Co. KG , Knollstrasse 50 , 67061 , Ludwigshafen , Germany.
  • Ding P; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States.
  • Dominguez E; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States.
  • DiGiammarino E; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Egan DA; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Freiberg GM; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Gopalakrishnan SM; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Harris CM; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States.
  • Honore MP; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Kage KL; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Kapecki NJ; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Ling C; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Ma J; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Mack H; AbbVie Deutschland GmbH & Co. KG , Knollstrasse 50 , 67061 , Ludwigshafen , Germany.
  • Mamo M; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Maurus S; AbbVie Deutschland GmbH & Co. KG , Knollstrasse 50 , 67061 , Ludwigshafen , Germany.
  • McRae B; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States.
  • Moore NS; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States.
  • Mueller BK; AbbVie Deutschland GmbH & Co. KG , Knollstrasse 50 , 67061 , Ludwigshafen , Germany.
  • Mueller R; AbbVie Deutschland GmbH & Co. KG , Knollstrasse 50 , 67061 , Ludwigshafen , Germany.
  • Namovic MT; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Patel K; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Pratt SD; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Putman CB; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Queeney KL; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States.
  • Sarris KK; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Schaffter LM; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States.
  • Stoll V; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Vasudevan A; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Wang L; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States.
  • Wang L; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States.
  • Wirthl W; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States.
  • Yach K; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States.
J Med Chem ; 61(24): 11074-11100, 2018 12 27.
Article en En | MEDLINE | ID: mdl-30384606
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inhibidores de Proteínas Quinasas / Quinasas Asociadas a rho Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: J Med Chem Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inhibidores de Proteínas Quinasas / Quinasas Asociadas a rho Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: J Med Chem Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos