Thalamic strokes that severely impair arousal extend into the brainstem.
Ann Neurol
; 84(6): 926-930, 2018 12.
Article
en En
| MEDLINE
| ID: mdl-30421457
ABSTRACT
In this study, we evaluate the role of the thalamus in the neural circuitry of arousal. Level of consciousness within the first 12 hours of a thalamic stroke is assessed with lesion symptom mapping. Impaired arousal correlates with lesions in the paramedian posterior thalamus near the centromedian and parafascicular nuclei, posterior hypothalamus, and midbrain tegmentum. All patients with severely impaired arousal (coma, stupor) had lesion extension into the midbrain and/or pontine tegmentum, whereas purely thalamic lesions did not severely impair arousal. These results are consistent with growing evidence that pathways most critical for human arousal lie outside the thalamus. Ann Neurol 2018;84926-930.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Tálamo
/
Tronco Encefálico
/
Coma
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Accidente Cerebrovascular
/
Estupor
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Ann Neurol
Año:
2018
Tipo del documento:
Article